
It's still recommended that you install the latest version of Power BI On-premises data gateway, as described earlier. You can instead successfully launch Power BI Desktop as administrator, which also allows Power BI Desktop to successfully open. Resolution 3: Run Power BI Desktop with administrator privilege

Or you can stop the Power BI On-premises data gateway Microsoft service, which removes the policy restriction and allows Power BI Desktop to open. You can uninstall the Power BI On-premises data gateway if you no longer need it. Resolution 2: Uninstall or stop the Power BI On-premises data gateway Microsoft service The link is a direct download link to the installation executable. You can download the latest version of Power BI On-premises data gateway. If you need to continue using Power BI On-premises data gateway, the recommended resolution is to update it. The latest version of the Power BI On-premises data gateway doesn't place named pipe restrictions on the local machine, and allows Power BI Desktop to open properly. You have three options to resolve the issue associated with the On-premises data gateway, and to enable Power BI Desktop to open: Resolution 1: Install the latest version of Power BI On-premises data gateway In Power BI Desktop, users who installed and are running previous versions of the Power BI On-premises data gateway can be blocked from opening Power BI Desktop, because of administrative policy restrictions that the Power BI on-premises gateway placed on named pipes on the local machine. Resolve issues with the On-premises data gateway and Power BI Desktop The latest version of Power BI Desktop supports information protection and can decrypt and open any encrypted PBIX file. You can download the latest version of Power BI Desktop (this link is a direct download link to the installation executable).

If you need to continue using Power BI Desktop, the recommended resolution is to update it to a version that supports information protection. You cannot open encrypted PBIX files using a Power BI Desktop version that does not support information protection. Resolve issues with opening encrypted PBIX files This article describes and provides a remedy for a number of circumstances where Power BI cannot open.
